Carbamazepine Induced Malformations

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Carbamazepine-induced hypogammaglobulinemia

Carbamazepine is used to control seizures. Its common side effects are sleep disorders, anorexia, nausea, vomiting, polydipsia, irritability, ataxia, and diplopia. Involvement of the immune system is rare, and few cases of decreased immunoglobulin levels have been reported. We describe a patient with low immunoglobulin levels due to carbamazepine use who presented with recurrent urinary tract i...

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Carbamazepine- induced hypertension.

A 33-year-old man with complex partial seizures developed de novo hypertension after the initiation of carbamazepine, which resolved on discontinuation. Although rare, a variety of cardiovascular effects including hypertension have been reported with carbamazepine. Numerous mechanisms may be responsible; however, shared pharmacologic properties with the tricyclic antidepressants are suspect. Hy...

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Carbamazepine (Tegretol)-induced thrombocytopenia.

A case of carbamazepine-induced thrombocytopenia is reported. The patient, a 38-year-old female, developed thrombocytopenia 10 days after receiving 400 mg carbamazepine daily. The presence of an anti-IgG carbamazepine-dependent platelet-reactive antibody was documented. Using flow cytometry, the drug-induced antibody was detected at a drug concentration as low as 10(-6) M.

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Carbamazepine induced pseudolymphoma syndrome.

syndrome: Recurrent "Cold" staphylococ-cal abscesses. Pseudolymphoma syndrome, as a hypersensitive reaction to anticonvulsant drugs especially phenytoin, carbamaze-pine, tridone and phenobarbitone is well known(l-4). Its pathogenesis is uncertain. It consists of a triad of fever, generalized rash and lymphadenopathy. Varying degrees of VOLUME 34-SEFTEMBER 1997 7. Hill HR, Quie PG. Raised IgE le...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1989

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-3-6-11